Can plavix and eliquis be given together

Find out if it is safe to take plavix and eliquis together, and what potential interactions or side effects may occur. Learn about the benefits and risks of combining these medications for your specific medical condition.

Combining Plavix and Eliquis: Is It Safe?

In recent years, there has been an increasing number of patients who require multiple medications to manage their health conditions. However, with the multitude of drugs available on the market, it is essential for healthcare professionals to be aware of potential drug interactions. One such combination that has raised concerns is the concurrent use of Plavix and Eliquis.

Plavix, also known as clopidogrel, is a commonly prescribed antiplatelet medication used to prevent blood clot formation. Eliquis, on the other hand, is a newer oral anticoagulant that belongs to the class of direct factor Xa inhibitors. Both drugs work to reduce the risk of blood clots, but they do so through different mechanisms.

Given the similarities in their therapeutic effects, many patients and healthcare providers wonder if Plavix and Eliquis can be safely used together. It is important to note that there is limited clinical data on the concomitant use of these two medications, and thus, the potential for drug interactions is not well understood. However, preliminary studies suggest that combining Plavix and Eliquis may increase the risk of bleeding, as both drugs inhibit blood clotting in different ways.

As a result, caution should be exercised when considering the simultaneous use of Plavix and Eliquis. Healthcare providers should carefully weigh the potential benefits against the risks and consider alternative treatment options, especially for patients who are at a high risk of bleeding or have a history of bleeding disorders. Close monitoring of the patient’s condition and regular assessment of their blood parameters is crucial to ensure their safety and well-being.

In conclusion, the concomitant use of Plavix and Eliquis should be approached with caution due to the potential risk of increased bleeding. Healthcare professionals should carefully evaluate the individual patient’s needs and consider alternative treatment options if necessary. Regular monitoring and communication with the patient are essential to ensure the best possible outcome.

Understanding Plavix and Eliquis

Plavix and Eliquis are both medications that are commonly prescribed to treat different medical conditions.

Plavix: Plavix, also known as clopidogrel, is an antiplatelet medication that is used to prevent blood clots. It is often prescribed to patients who have recently had a heart attack or stroke, or who have certain heart or blood vessel conditions. Plavix works by preventing platelets in the blood from sticking together and forming clots.

Eliquis: Eliquis, also known as apixaban, is an anticoagulant medication that is used to prevent blood clots. It is often prescribed to patients who have atrial fibrillation (an irregular heartbeat) or who have had hip or knee replacement surgery. Eliquis works by inhibiting the activity of certain clotting proteins in the blood, reducing the risk of clot formation.

While both Plavix and Eliquis are used to prevent blood clots, they work in different ways and have different mechanisms of action. Plavix is an antiplatelet medication, while Eliquis is an anticoagulant medication.

It is important to note that Plavix and Eliquis can have different side effects and may interact with other medications differently. It is crucial for patients to consult with their healthcare provider before taking these medications together or making any changes to their medication regimen.

Disclaimer: The information provided in this article is for informational purposes only and should not be considered as medical advice. Always consult with a qualified healthcare professional before making any medical decisions.

Potential Interactions between Plavix and Eliquis

Plavix (clopidogrel) and Eliquis (apixaban) are both medications commonly used to prevent blood clots. Plavix is an antiplatelet drug that helps prevent platelets from sticking together and forming clots, while Eliquis is an anticoagulant that works by inhibiting specific clotting factors.

While Plavix and Eliquis are often prescribed together for patients who have certain medical conditions, it is important to be aware of potential interactions between these two medications. Although there are no direct contraindications for using Plavix and Eliquis together, caution should be exercised due to the potential for increased bleeding risk.

Both Plavix and Eliquis can increase the risk of bleeding on their own, and when used together, this risk may be further amplified. It is crucial to consider the individual patient’s medical history, including any previous bleeding episodes or blood disorders, before prescribing these medications together.

Additionally, since both Plavix and Eliquis are metabolized in the liver, there is a potential for drug-drug interactions. Plavix is primarily metabolized by the enzyme CYP2C19, while Eliquis is metabolized by CYP3A4 and P-gp. Co-administration of these medications may lead to altered levels of one or both drugs in the body, potentially impacting their effectiveness or increasing the risk of side effects.

Close monitoring of patients receiving Plavix and Eliquis together is essential. Regular blood tests to assess clotting function, as well as liver function, should be performed to ensure that the medications are being well-tolerated and are achieving their intended therapeutic effects.

In conclusion, while Plavix and Eliquis can be given together in certain cases, it is crucial to carefully consider the potential interactions and closely monitor patients for any signs of increased bleeding or altered drug levels. Healthcare professionals should communicate with patients about the risks and benefits of using these medications together and ensure that any potential interactions are managed effectively.

Effects of Combining Plavix and Eliquis

When considering the effects of combining Plavix and Eliquis, it is important to understand how these medications work individually and how they may interact when used together. Plavix (clopidogrel) is an antiplatelet medication that helps prevent blood clots by inhibiting the activity of platelets, while Eliquis (apixaban) is an anticoagulant that works by inhibiting the activity of certain clotting factors.

Potential Benefits

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When used together, Plavix and Eliquis may provide additional protection against blood clots for individuals at high risk. The combination of an antiplatelet agent (Plavix) and an anticoagulant (Eliquis) may help prevent the formation of blood clots in different ways, targeting multiple pathways involved in clot formation.

Additionally, combining Plavix and Eliquis may be beneficial for individuals who have undergone certain medical procedures, such as stent placement or cardiac surgery. The dual antiplatelet and anticoagulant therapy may reduce the risk of clot formation around the implanted device or surgical site.

Potential Risks

Combining Plavix and Eliquis also carries potential risks, as these medications can increase the risk of bleeding. Both Plavix and Eliquis can independently cause bleeding, and using them together may further increase this risk.

It is important for healthcare professionals to carefully consider the individual patient’s medical history, current medications, and overall health status when deciding to combine Plavix and Eliquis. Close monitoring and dose adjustments may be necessary to minimize the risk of bleeding complications.

Furthermore, it is essential to follow the prescribed dosage and schedule for both medications to ensure their safe and effective use. Any changes or adjustments to the treatment regimen should be made under the guidance and supervision of a healthcare professional.

Conclusion

Combining Plavix and Eliquis may offer potential benefits in certain high-risk individuals or specific medical situations, such as post-surgical care. However, it also carries the risk of increased bleeding. The decision to use these medications together should be based on a careful assessment of the individual patient’s needs and the potential risks and benefits. Healthcare professionals should closely monitor patients who are prescribed both Plavix and Eliquis to ensure their safety and optimize their treatment outcomes.

Considerations for Patients Taking Plavix and Eliquis

When considering the use of Plavix and Eliquis together, it is important for patients and healthcare providers to be aware of potential drug interactions and the associated risks. Both medications are commonly prescribed for different medical conditions, but they work in different ways and can affect the body differently.

Plavix is a medication that belongs to a class of drugs called antiplatelets. It is typically used to reduce the risk of heart attack, stroke, and other cardiovascular events by preventing blood clots from forming. Eliquis, on the other hand, is an anticoagulant medication and belongs to a class of drugs called direct oral anticoagulants (DOACs). It is primarily used to reduce the risk of stroke and blood clots in patients with atrial fibrillation.

While Plavix and Eliquis are used for different indications, there may be situations where a patient may require both medications. In such cases, it is crucial for healthcare providers to carefully consider the potential drug interactions and the overall benefit-risk profile for the patient.

Potential Drug Interactions
Risk Assessment
Plavix and Eliquis both have the potential to increase the risk of bleeding. Patients taking both medications may have an increased risk of bleeding complications. Close monitoring for signs of bleeding is essential.
Plavix may reduce the effectiveness of Eliquis. Patients taking both medications may have a reduced anticoagulant effect of Eliquis. Dose adjustments or alternative treatment options should be considered.
Other medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs) or selective serotonin reuptake inhibitors (SSRIs), may further increase the risk of bleeding when combined with Plavix and Eliquis. Patients should be cautious when taking additional medications that can increase the risk of bleeding. Healthcare providers should review the patient’s complete medication list and consider alternative treatment options if necessary.

In summary, the use of Plavix and Eliquis together requires careful consideration and monitoring due to potential drug interactions and increased risk of bleeding. Healthcare providers should assess the individual patient’s medical history, current medications, and overall risk profile before prescribing both medications concurrently. Regular follow-up and close monitoring are essential to ensure patient safety and optimize treatment outcomes.

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Brandi Shotwell

Brandi Shotwell is a Principal at Reno Capital Management in Dallas, Texas concentrating on debt and equity. With over 20 years’ experience in finance and real estate, Brandi has had leadership involvement in over $1 billion in real estate projects ranging from commercial acquisitions to commercial development.  She has organized funding acquisitions and development opportunities for multifamily investors, high net worth individuals, municipal growth areas, and manufacturing clients. Prior to joining RCM, Brandi was Vice President at Edge Capital Markets in Dallas, Texas.  Preceding Edge, she was Vice President of Coronado Bay Capital where she was the top producing originator of the company.  Previously, she was a founding partner of Global Mortgage USA. Brandi attended Purdue University Northwest where she studied business and marketing.

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Dugan Kelley, Real Estate & SEC Attorney

Dugan P. Kelley co-founded Kelley Clarke, PC with the mission to deliver big firm expertise and experience to the local community. Kelley Clarke currently serves clients throughout the United States with its principal offices in Prosper, Texas and Santa Barbara, California. Mr. Kelley chairs the firm’s securities and real estate practice group, assisting clients in all phases of multi-family, commercial, and residential acquisitions or sales. Throughout Mr. Kelley’s career, he has assisted clients in structuring real estate transactions in excess of $2 Billion. Currently, Mr. Kelley provides syndication and securities services for clients throughout the United States, assisting clients in all phases of their acquisition and sale of commercial and residential real-estate assets.

Mr. Kelley’s real estate expertise includes transactional services for his clients ranging from commercial loan closings, real estate private equity capital raises, joint venture agreements, commercial leasing, business acquisitions and general commercial real estate services for multi-family syndicators, investors, and developers.

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Mr. Kelley was previously a partner with Cappello & Noel, one of the nation’s foremost complex commercial litigation firms, in Santa Barbara, California. While at Cappello, Mr. Kelley successfully prosecuted and defended major commercial litigation involving a variety of commercial matters including lender liability, contract and transactional disputes, and fraud. Prior to his tenure at Cappello, Mr. Kelley was a litigator at Bonne, Bridges, Mueller, O’Keefe & Nichols in Los Angeles where he successfully defended healthcare professionals and healthcare institutions involved in malpractice suits. Mr. Kelley’s practice also included defending employment claims against professionals and the County of Los Angeles. Prior to moving into the civil sector, Mr. Kelley successfully prosecuted criminal matters.

In addition, for several years, Mr. Kelley was an adjunct law professor teaching fundamental legal skills, legal research and writing, and moot court to law students in the Orange County area. From 2008 through 2016, Mr. Kelley has been selected as a “Super Lawyer Rising Star,” with only 2.5% of attorneys recognized as the best attorneys. Mr. Kelley routinely acts as a mediator for other attorneys or as settlement counsel for complex litigation matters that require a unique solution. Mr. Kelley is a best selling author of Purpose, Passion & Profit and is frequent speaker and lecturer at events. He also serves on a number of non-profit Boards, including Treasured Vessels Foundation, which has a purpose for ending human sex trafficking and providing shelter to those victims of human sex trafficking.

Mr. Kelley and his wife, Michelle have 3 boys. The entire Kelley family is actively involved in giving back to their local church and community.  Contact Kelley | Clarke to help you in your next transaction.

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Brent Kawakami, PE

Brent is a real estate investor, entrepreneur, and a Registered Professional Engineer in the State of Texas with extensive experience in acquisitions and underwriting of properties in the multi-family arena.

Mr. Kawakami has been investing in Real Estate since 2012 where he focused on buying, rehabbing, and renting single family rentals in the Dallas, Texas area. In 2015, he began his transition from single family to multi-family where he has acquired over 450+ multi-family units across, Texas, Georgia, Kansas, and Ohio. His current focus is acquisitions and works closely with many syndicators to help vette and determine through critical analysis of underwriting and reviewing market factors to determine if a property is a go or no go for pursuing with a Letter of Intent. At the same time, he works with Sellers Brokers nationwide to help foster relationships for syndicators in key market areas.

As a result, of his experience and top-notch reputation, this has allowed him to become an integral team member of General Partnerships when underwriting private placement transactions for the syndicate team as well as providing transactional support through quantitative proforma models.

Mr. Kawakami graduated with a Bachelor of Science in Electrical Engineering from the University of Texas in Austin. Mr. Kawakami is originally from Hawaii and currently resides in the DFW Metroplex. Brent also spent over 13+ years in the private sector where he worked as consultant engineer in the power/energy industry, working in various roles in design, construction, and project management. Brent has led numerous multi-million dollar projects and has been responsible for the development of over $1B in construction projects for such leading edge companies such as Oncor.

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Mark Kenney

Mark Kenney is a seasoned real estate investor, entrepreneur and founder of Think Multifamily along with his wife Tamiel. Mr. Kenney started his real estate career over 20 years ago and has extensive experience in property valuation, acquisition, and operations. He has a passion for helping others succeed in the multi-family arena.

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Karla Gonzales, FINRA Series 7, 50, 52 & 63

Karla is an entrepreneur, Real Estate Investor, and experienced Investment Banker and a Vice President with a well-known Wall Street investment banking firm. She currently is a Registered Representative with the following licenses through FINRA: Series 7, Series 50, Series 52, and Series 63. In the last six years, she has completed nearly 200 municipal bond financings totaling more than $4.0 billion.

As a result, of this experience and top-notch reputation, this has allowed her to become an integral team member of the General Partnership when underwriting private placement transactions for the syndicate team as well as providing transactional support through quantitative proforma models. Her skillset also allows her to be involved in preparing investor presentations, attending and presenting before potential clients, and fostering ongoing client relationships with multi-family investors.

Ms. Gonzales graduated Cum Laude with a Bachelor of Science in Finance from the University of Texas at Dallas. She is currently invested in single family and multi-family properties with over 900+ units in Texas, Georgia, Kansas, and North Carolina. Ms. Gonzales is originally from Michoacán, Mexico and is fluent in both English and Spanish helping to serve our Spanish speaking investors.

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Robert Gonzales, AIA, IIDA, LEED® AP BD+C

R

ob Gonzales, AIA, LEED® AP BD+C, is a Real Estate Developer for one of the top real estate firms in Dallas-Ft. Worth Metroplex where he develops and manages the infill of Class A+ luxury multifamily communities with first-class amenities in Dallas, San Antonio, Austin, Ft. Worth, Midland, Irving, Frisco, College Station, Mansfield, Leander, Colorado Springs, CO, Phoenix, AZ, and the Carolinas.

Mr. Gonzales is also an entrepreneur, real investor, and has over 16+ years of Project and Management experience as a Registered Architect, Registered Interior Designer, and Commercial General Contractor, including 11 years as a LEED® Accredited professional with a specialization in Building Design & Construction.  His experience includes work on over 80+ major vertical building projects and facilities valued at over $1.90 billion dollars.

Mr. Gonzales’ project experience, design background, graphics capability, and experience with multi-family commercial construction among other facilities allows him to be as asset providing cost-effective solutions during the due diligence period when collaborating with the General Partnership for decisions involving design challenges, rebranding, design, and constructability reviews. In addition, Mr. Gonzales helps provide transactional support to the General Partnership when underwriting private placement transactions for the syndicate team by keying on his skills that he gained earlier in his career by working as an Investment Banker and Registered Representative for a well-known Wall Street firm. 

Mr. Gonzales currently operates in the capacity of Team principal/General Partner and Asset Manager (i.e. Operator) on over 1,200+ units in 6 states across the southeast (i.e. Texas, Kansas, Georgia, Arkansas, North Carolina, and Florida) with a reputation among the multi-family investment community as having the ability to source deals, underwrite/analyze deals, be an effective Operator, Capital Raiser, and providing cost-effective design solutions, and focuses much of his time rebranding, and repositioning properties.

Mr. Gonzales received his Bachelor of Arts and Master of Architecture degree from Texas A&M University. He is currently invested in single family and multi-family properties while making his home in both Texas and Florida having lived in Austin, San Antonio, Houston, Tampa, and South Florida (including Weston, Ft. Lauderdale, and Miami), and now having recently returned back to Dallas in the past 5 years.